The authors of this article investigated Rejuvenate hip implant failures in order to identify patients who are at particularly high risk for developing adverse tissue reactions (ALTR). They also wanted to determine how accurate MRI and metal ion levels are in detecting ALTR. The results confirmed that females and small Rejuvenate stem sizes were at a higher risk of early failure as a result of a symptomatic pseudotumor within 3 years of follow-up. No one can seem to explain however, why some people with low cobalt-chromium levels and no pseudotumors develop symptoms, while some patients with high metal levels and pseudotumors remain asymptomatic.  The authors found that cobalt and chromium levels were not as accurate in identifying ALTR as MRI. Dr. Ghanem and his colleagues felt that the potential for developing complications with dual modular stems, such as the Rejuvenate outweighs their benefits.

Ghanem, E. et al. (2015). Corrosion and Adverse Local Tissue Reaction in One Type of Modular Neck Stem, Journal of Arthroplasty, Epub